Dermatology Update 2017 Fall
SESSIONS & ABSTRACTS
VANCOUVER, FAIRMONT WATERFRONT HOTEL - OCTOBER 26-29, 2017
Palmoplantar Keratodermas- update on diagnosis and management
Centre for Cell Biology and Cutaneous Research, Blizard Institute, Queen Mary University of London and Department of Dermatology, Royal London Hospital, Barts Health NHS Trust, London, UK
This lecture will focus on the hereditary palmoplantar keratodermas (PPK), a heterogeneous group of disorders characterized by hyperkeratosis of palmoplantar skin. The PPKs can be divided into 3 groups according to the clinical pattern of the hyperkeratosis including diffuse, focal (which includes striate) and punctate PPK. Affected individuals may have a simple PPK without associated features, or a syndromic PPK with associated features, such as hearing loss, cardiomyopathy, hair, dentition or nail changes. In recent years, many causative genes of PPK have been identified, which has confirmed and/or altered the traditional clinical classification. The role of histology of a palmar biopsy and genetic testing will be discussed. Finally, new approaches to treatment will be summarized.